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Updated: May 27 2017

Inhaled Muscarinic-Antagonists

Overview
  • Therapeutic strategies for treating asthma are via
    • decreasing inflammation
    • increasing sympathetic tone
  • There are 7 families of drugs that are commonly used:
    1. corticosteroids
    2. β-agonists
    3. muscarinic antagonists
    4. methylxanthines
    5. cromolyn
    6. antileukotrienes
    7. omalizumab
Muscarinic antagonists
  • Drugs
    • ipratropium 
  • Mechanism
    • competitive inhibition of muscarinic receptors 
      • prevents bronchoconstriction
  • Also used for COPD  
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