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Updated: May 9 2017

Torsades de Pointes

Snapshot
  • Torsades A man with a family history of sudden cardiac death is brought in by EMS after collapsing on the basketball court. His EKG tracing from the EMS team is shown.
Introduction
  • A form of polymorphic ventricular tachycardia
    • early after depolarization 
    • progressive, sinusoidal, cyclic alteration of the QRS axis
    • peaks of QRS seem to "twist"
  • Causes include
    • hypomagnesemia, hypokalemia, hypocalcemia
    • prolonged QT interval due to any cause
      • includes Class IA and Class III antiarrhytmics (except amiodarone), tricyclic antidepressants
    • congenital long QT syndromes 
      • Jervell and Lange-Nielsen syndrome 
        • due to defects in cardiac sodium or potassium channels
        • can be associated with congenital sensorineural deafness
Presentation
  • Symptoms/Physical exam
    • syncope
    • palpitations
    • cardiogenic shock
    • sudden cardiac death
Evaluation
  • ABCs with advanced cardiac life support
Treatment
  • Often shortlived and self-terminating
  • Discontinue all QT prolonging drugs
  • Defibrillation
  • If hypokalemic 
    •  magnesium sulfate 
  • If refractory
    • isoproterenol
    • transvenous pacing

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