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Updated: Mar 30 2017

Dilated Cardiomyopathy

Snapshot
  • A 57-year-old man presents to the emergency department complaining of chest pain and swollen feet three days after visiting his family for the holidays. He has a history of chronic alcohol abuse.
Introduction
  • Overview
    • most common form of cardiomyopaty
    • dilated cardiomyopathy leads to systolic dysfunction
  • Etiology 
    • alcohol abuse  
    • beriberi
    • Chagas' disease (in South America)
    • coxsackievirus (postviral myocarditis) 
    • cocaine use
    • doxorubicin toxicity
    • hypertension
    • ischemia
    • peripartum cardiomyopathy
    • tachycardia
Presentation
  • Symptoms
    • dilated cardiomyopathy, like other forms, may present as
      • acute onset
      • slowly progessive symptoms
    • symptoms include
      • exertional dyspnea
      • edema
      • fatigue
      • loss of appetite
      • cough
  • Physical exam
    • classic signs of CHF
      • swelling legs
      • lung sounds
      • JVD
    • hepatomegaly
Evaluation
  • Echocardiography
    • is most definitive diagnosis
    • shows dilated ventricles 
    • confirms decreased EF
  • CXR
    • often shows balloon-like heart
Differential
  • Other cardiomyopathies, and other causes of CHF TakoTsubo scheme.png
    • Takotsubo cardiomyopathy (transient apical ballooning syndrome aka stress induced cardiomyopathy) 
      • Classic "heart break" disease - induced by stress (ventricular wall weakening, decreased contractility)
      • Takutsubo = Japanese octopus trap (heart resembles these traps)
      • Treatment
        • Tends to self resolve in months - usually supportive therapy
        • β-blockers and aspirin can be helpful
Treatment
  • Nonoperative
    • medications directed at improving cardiac function
      • ACEIs/ARBs
      • β-blockers
      • spironolactone
      • digoxin 
        • for symptom improvement - does not improve mortality
Prevention, Prognosis, and Complications
  • Prognosis
    • good with appropriate treatment and lifestyle modifications
  • Prevention
    • diet and exercise
    • smoking cessation
    • limit alcohol intake
  • Complications
    • arrhythmias
    • CHF
    • pulmonary edema
    • side effects of CHF medications
Question
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