Please confirm topic selection

Are you sure you want to trigger topic in your Anconeus AI algorithm?

Please confirm action

You are done for today with this topic.

Would you like to start learning session with this topic items scheduled for future?

Updated: May 20 2015

Antileukotrienes

Overview
  • Therapeutic strategies for treating asthma are via
    • decreasing inflammation
    • increasing sympathetic tone
  • There are 7 families of drugs that are commonly used:
    1. corticosteroids
    2. β-agonists
    3. muscarinic antagonists
    4. methylxanthines
    5. cromolyn
    6. antileukotrienes
    7. omalizumab
Antileukotrienes
  • Drugs
    • zileuton
      • 5-lipoxygenase pathway inhibitor
        • blocks conversion of arachidonic acid to leukotrienes
    • zafirlukast, montelukast
      • blocks leukotriene receptors
      • particularly effective in aspirin-induced asthma
Private Note